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Mesothelioma and Lung
Cancer Information Center
Advanced Cancer Help is part of the Renaissance
Healthcare Systems network and is dedicated giving our patients
and their families the best quality healthcare available. We invite you to
join us in sharing your information in the
battle against mesothelioma. With the latest
news and information regarding mesothelioma treatment, clinical trials, research
and cancer survivors.
Renaissance Healthcare offers both medical assistance for you or your loved one and legal
assistance through specialized mesothelioma attorneys. Our primary concern
is treatment of the overall patient and seeking to provide the highest "whole
life" care. Patients who have been diagnosed with mesothelioma or asbestosis
can receive financial settlements to help them offset patient care costs.
For our assistance in finding a quality treatment program and finding a qualified
mesothelioma attorney please fill out our contact form and someone from our staff
will review you case and offer get you or your loved one the assistance they need..
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Types
of Mesothelioma:
Pleural mesothelioma
is a cancer of the cells that make up the pleura or lining around the outside of
the lungs and inside of the ribs. Its only known cause in the U.S. is previous exposure
to asbestos fibers, including chrysotile, amosite or crocidolite. This exposure
is likely to have happened twenty or more years before the disease becomes evident,
since it takes many years for the disease to "incubate." It is the most
common type of mesothelioma, accounting for about 75% of all cases.
Benign mesothelioma can often be removed surgically,
are generally not life-threatening, and are not usually related to asbestos exposure.
Malignant mesothelioma, however, are very serious. Fortunately, they are rare -
about two thousand people are diagnosed with mesothelioma in the U.S. each year.
Many of the organs in the abdomen are enveloped
by a thin membrane of mesothelial cells, known as the peritoneum.
Peritoneal mesothelioma
is a tumor of this membrane. Its only known cause in the U.S. is previous exposure
to asbestos, but it can be many years after exposure before the disease appears.
Peritoneal mesothelioma account for about one-fifth of all mesothelioma.
Pericardial Mesothelioma
is a tumor that can occur at any age with a mean age of 46 years at presentation.
Patients present with chest pain, dyspnea, cough, and palpitations. Although there
appears to be a strong link to asbestos exposure, a definite association has not
been established due to the rarity of this lesion. Surgery combined with radiation
therapy may provide some palliation, but the prognosis is extremely poor. On CT
there is irregular, diffuse pericardial thickening and a pericardial effusion. Pericardium
is a thin lining of tissue surrounding the heart.
Symptoms of Mesothelioma:
When the symptoms of peritoneal mesothelioma appear, they typically include
abdominal pains, weakness, weight loss, loss of appetite, nausea, and abdominal
swelling. Fluid often accumulates in the peritoneal space, a condition known as
ascites. Over time the wasting symptoms can become more and more severe.
The growing tumor can exert increasing pressure on the organs in the
abdomen, leading to bowel obstruction and distention. If the tumor presses upward,
it can impair breathing capacity. If the tumor pushes against areas with many nerve
fibers, and the bowel distends, the amount of pain can increase.
Treating Mesothelioma:
The treatment options for people with mesothelioma
have improved significantly, especially for those whose cancer is diagnosed early
and treated vigorously. Many people are treated with a combination of therapies,
sometimes known as multimodal therapy.
Specific types of treatment include:
There are also experimental treatments like gene therapy and immunotherapy, angiogenesis
inhibitors, and clinical trials for various new treatments and combinations of treatments.
Treatments that reduce pain and improve lung function, are becoming more successful
(although they cannot cure mesothelioma.) Pain control medications have become easier
to administer. Debulking is a surgical process of removing a substantial part of
the tumor and reducing the pleural thickening; this can provide significant relief.
X-ray therapy has also been successfully used to control the tumor and the pain
associated with it for a while.
Surgery is a common treatment of
malignant mesothelioma. The doctor may remove part of the lining of the chest
or abdomen and some of the tissue around it. Depending on how far the cancer has
spread, a lung also may be removed in an operation called a pneumonectomy. Sometimes
part of the diaphragm, the muscle below the lungs that helps with breathing, is
also removed.
Radiation therapy uses high-energy x-rays to kill cancer cells and shrink tumors.
Radiation may come from a machine outside the body (external radiation therapy)
or from putting materials that produce radiation (radioisotopes) through thin plastic
tubes in the area where the cancer cells are found (internal radiation therapy).
Mesothelioma Research:
There is as yet no known cure for
malignant mesothelioma. The prognosis depends on various factors, including
the size and stage of the tumor, the extent of the tumor, the cell type, and whether
or not the tumor responds to treatment. KMESA has represented many clients who lived
for five to ten years after diagnosis, most of them in good health for a majority
of those years. Some mesothelioma victims succumb within a few months; the average
survival time is about a year.
X-rays and CT scans are, typically, the first step towards detecting peritoneal
mesothelioma. The actual diagnosis is typically achieved by obtaining a piece of
tissue. The medical procedure of looking at the peritoneum is known as a peritoneoscopy.
It is a hospital procedure and requires anesthesia. If an abnormality is seen, the
doctor will attempt to obtain a tissue sample - this is known as a biopsy. The tissue
sample will be examined by a pathologist who makes a diagnosis using microscopic
analysis of specialized stains.
There are at least two explanations for how asbestos fibers can get into the peritoneum.
The first is that fibers caught by the mucus of the trachea and bronchi end up being
swallowed. Some of them lodge in the intestinal tract and from there they can move
through the intestinal wall into the peritoneum. The second explanation is that
fibers that lodge in the lungs can move into the lymphatic system and be transported
to the peritoneum.

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