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MALIGNANT MESOTHELIOMA
What is Malignant Mesothelioma?
Malignant mesothelioma is a cancerous tumor of the lining of the lung and
chest cavity (pleura) or lining of the abdomen (peritoneum) that is almost
always caused by sustained exposure to asbestos.
Malignant mesothelioma is a diffuse tumor that affects men more frequently
than women. Sustained exposure to asbestos is the predominant risk factor.
However, smoking dramatically increases risk amongst the asbestos-exposed.
The latent period between asbestos exposure and onset of symptoms can be
20 to 50 years or even longer.
The median age of diagnosis is 60. The tumor can spread rapidly to involve
the pericardium (sac around the heart), mediastinum, and opposite pleura.
Progressive pain and shortness of breath can occur. The tumor is usually
associated with a pleural effusion.
Differentiation of the tumor from other conditions of the pleura and other
types of cancer can be difficult, even when experienced pathologists are
viewing biopsy samples.
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